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Staff Scientist I-Antibody Reagent and Discovery
Company | LabCorp |
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Location | Wyomissing, PA, USA |
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Salary | $85000 – $105000 |
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Type | Full-Time |
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Degrees | Master’s, PhD |
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Experience Level | Senior |
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Requirements
- Minimum of a Master’s degree with 5-7 years of relevant experience
- Ph.D. in Immunology or related biological science with a strong focus on antibody-based research preferred
- A minimum of 2-5 years of industry experience in antibody-based studies for therapeutics
- Extensive hands-on experience in the development, optimization, and validation of antibodies (e.g., AKTA FPLC purification, Meso Scale Discovery and other immune-based techniques)
- Demonstrated ability to lead and manage complex scientific projects and multidisciplinary teams
- Excellent communication skills with the ability to convey complex scientific concepts to both technical and non-technical stakeholders
- Proficiency in using scientific software and laboratory automation tools
Responsibilities
- Execute and oversee antibody and antibody variant (e.g., Fab, scFv, full-length IgG) generation and purification campaigns
- Contribute to the development and optimization of antigen preparation strategies (e.g., recombinant protein expression – eukaryotic and mammalian systems)
- Perform and contribute to hybridoma and single B cell cloning methods for monoclonal antibody campaigns
- Characterize binding specificity, affinity, and cross-reactivity of antibody reagents using ELISA, SPR/BLI and other immunoassays
- Analyze complex data, prepare reports, and present findings to internal and external stakeholders
- Mentor and lead junior scientists and provide guidance in assay development, data interpretation, and troubleshooting
- Collaborate with other groups within Labcorp to ensure seamless integration of ARV services into product development programs
- Stay current with scientific advances in antibody discovery and reagent technologies
Preferred Qualifications
- Experience with gene therapies, biosimilars, display technologies or novel biologics
- Knowledge of regulatory guidance for Anti-Drug Antibody and PK testing for biologics
- Experience with assay development in a GLP environment