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Staff Computational Biologist

Staff Computational Biologist

CompanyFreenome
LocationDaly City, CA, USA
Salary$161925 – $247000
TypeFull-Time
DegreesMaster’s, PhD
Experience LevelSenior

Requirements

  • Post-graduate degree (MS or PhD) in statistics, computational biology, bioinformatics, cancer biology, or related quantitative field
  • 3+ years of industry experience
  • Experience with molecular biology
  • Experience in experimental design and analysis of high-throughput, quantitative technologies
  • Familiarity with and ability to select and leverage bioinformatics tools for the above molecular assays
  • Experience in applied statistics, such as in hypothesis testing, GLM, and appropriate use of simulation
  • Expertise in data analysis and visualization using R (tidyverse), or Python statistical packages (Numpy, Matplotlib, Pandas), or equivalent, under version control
  • Excellent oral and written communication skills to communicate to scientific and broader audiences, with keen attention to detail
  • Ability to work on a cross-functional team in our highly collaborative environment, working with both computational and experimental scientists

Responsibilities

  • Plan and execute development experiments for Freenome’s multiomics cancer screening tests
  • Partner cross-functionally with computational, development, regulatory, and quality leaders to develop and execute a regulated development strategy working toward FDA approval
  • Use your quantitative skills to develop computational methods and interpret complex experimental results in order to optimize and validate innovative technology for sample collection, preparation, and detection
  • Develop and execute appropriate experimental design and analysis plans for Development, Verification, and Validation studies, closely partnering with Biostatistics, Development, and Pre-Analytics teams
  • Work closely with molecular and computational research teams developing Freenome’s IVD products for blood-based molecular assays involving cell-free DNA
  • Impact patient lives through the development and launch of high quality cancer screening technologies

Preferred Qualifications

  • Experience in the development of diagnostic devices in a regulated environment (PMA, 510(k), CE-IVD) preferred
  • Experience with different NGS methods (e.g. target capture with UMI, Hi-C, ATAC-seq, RNA-seq, bisulfite sequencing, microarrays)