Senior Scientist – Analytical Research & Development
| Company | Merck |
|---|---|
| Location | Linden, NJ, USA |
| Salary | $114700 – $180500 |
| Type | Full-Time |
| Degrees | Master’s, PhD |
| Experience Level | Junior, Mid Level, Senior |
Requirements
- Ph.D. in Analytical Chemistry, Biological Sciences or related discipline in the field of mass spectrometry with 0+ years of experience (with expected completion by August 2025)
- Candidates with a MS degree and 4+ years of relevant experience will also be considered
- Extensive experience in structural elucidation across modalities by LC-MS/MS
- Experience conducting tandem mass spectrometry experiments on HRMS, including sample preparation and optimization, mass spectrometer operation and maintenance, and data interpretation and analysis
- Familiarity with Genedata or other MS software
- Excellent oral and written communication skills
- Proven track record of peer-reviewed publications
Responsibilities
- Structural elucidation of unknown impurities and degradation products of small molecules, peptides, bioconjugates by developing novel LC HRMS methods
- Represent the mass spectrometry group in project teams
- Author technical reports and scientific presentations
- Explore and develop new technologies applicable to our field
- Perform data processing with Genedata or other data interpretation software
- Demonstrate effective multitasking, prioritization and problem-solving skills in the planning and execution of experiments
Preferred Qualifications
- Experience in organic chemistry
- Experience in LC-MS based assays including peptide mapping, intact mass, proteomics, and host cell protein analysis characterization for protein engineering
- Experience in molecular imaging, e.g. MALDI imaging on a Bruker tims TOF fleX
- Hands on experience in protein sample preparation for MS analysis and top-down protein characterization on Thermo Orbitrap MS system
- Experience in 2D LC/MS instrumentation
- Ability to write computer software for automated data interpretation