Senior Principal Scientist – Pancreatic Cancer Disease Lead – Translational Development
| Company | Bristol Myers Squibb |
|---|---|
| Location | Cambridge, MA, USA, Princeton, NJ, USA |
| Salary | $Not Provided – $Not Provided |
| Type | Full-Time |
| Degrees | PhD |
| Experience Level | Senior, Expert or higher |
Requirements
- PhD degree in a relevant field (e.g. molecular biology, cancer biology, human genetics)
- 4+ years post-PhD experience, with demonstrated scientific leadership in integrating, analyzing and interpreting multimodal translational data in an academic and/or industry setting
- Strong background in human cancer genetics, tumor biology & immunology, genomics/multi-omics with deep understanding of tumor-intrinsic and tumor-extrinsic mechanisms driving cancer development and therapeutic resistance
- Extensive knowledge of high-content biomarker platforms and good understanding of the current clinical practice in Pancreatic Cancer
- Ability to work in a fast-paced environment with rapidly changing and competing priorities and ambiguity
- Strong team player with the ability to work in cross-functional teams. Excellent communication and collaboration skills
Responsibilities
- Develops and executes translational disease strategy in the pancreatic cancer (PC) area with deep disease expertise
- Leads and oversees execution of disease strategy including but not limited to various aspects of patient selection strategies
- Serves as scientific expert in generating novel hypotheses for actionable biology based on novel discoveries integrating disease work with literature and deep expertise in PC biology
- Manages cross-functional disease project teams with key interfaces in IT, bioinformatics, data sciences, biostatistics, external collaborators, contractors, other disease strategy leads and asset leads
- Maintains relationship with physician scientists for identifying new opportunities and for gaining disease insights
- Identifies needs, gaps and translational disease questions and applies knowledge across all assets in BMS portfolio in the PC area
- Leads small and large collaborations with academia and industry partners to identify biobanks, clinical trials and existing databases to collate multi-parameter genomic, immune and clinical datasets to mine for novel biomarkers of unmet need patients in conjunction with computational biologists, data scientists and statisticians
- Collaborates and guides bioinformatics partners on biological questions to deliver biomarkers and biological understanding from whole transcriptome, whole exome, and/or whole genome data, immune profile and single-cell data to support drug discovery and development in the PC space
- Manages relationships with key internal stakeholders including Regulatory, Clinical, Commercial, Medical Affairs & Communications and external collaborators to develop translational analysis plans and timelines, communicate analysis results
- Represents the Solid Tumor Translational Development function at various internal meetings and provide domain knowledge and disease expertise to cross-functional teams
- Directs and supports publications in high quality scientific, technical or medical journals
Preferred Qualifications
- Prior experience with clinical trials preferred
- Strong track record of high-quality scientific publications in relevant fields