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Senior Principal Scientist I – Quantitative Pharmacology
| Company | Sanofi |
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| Location | Cambridge, MA, USA |
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| Salary | $147000 – $212333.33 |
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| Type | Full-Time |
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| Degrees | PhD |
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| Experience Level | Senior, Expert or higher |
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Requirements
- A Ph.D. in Pharmacokinetics or other relevant field + a minimum of 7 years relevant experience
- The ability to function in a matrix and global environment
- Experience supporting NBE therapeutics
- Ability to drive and lead PK, PKPD and ADME strategies for discovery project teams
- Knowledge of and/or ability to conduct non-compartmental analysis (NCA) for non-GLP PK and TK reports
- Experience with pharmacokinetics, pharmacometrics, PKPD relationships, bioanalytical techniques and/or ADME principles in a drug discovery setting
- Willingness to grow and learn into role
- Strong written, presentation and verbal communication skills are essential
- Strong leadership and teamwork skills
Responsibilities
- Characterize the ADME and PK properties for diverse modalities (primarily biotherapeutics)
- Conceive and implement the preclinical PKPD strategy for a drug and/or target
- Representing QP and the TMU on cross functional project teams as a project team leader
- Conceive and implement the strategy towards predicting efficacious and safe human dose levels
- Support the QP organization by addressing critical knowledge gaps
Preferred Qualifications
- Experience with protein engineering concepts
- Experience with modeling & simulation concepts
