Senior Director – Protein Sciences
| Company | Flagship Pioneering |
|---|---|
| Location | Boston, MA, USA |
| Salary | $Not Provided – $Not Provided |
| Type | Full-Time |
| Degrees | PhD |
| Experience Level | Senior, Expert or higher |
Requirements
- PhD in biochemistry, molecular or structural biology, or related disciplines with at least 10 years post-PhD research experience, 5 of which in a biotech or large Pharma setting
- Expertise and in-depth knowledge of antibody, bispecifics and Fc fusion design, expression and production, with a strong track record in advancing programs in an industry setting
- Extensive hands-on industry expertise in biochemical, biophysical and structural characterization of antibody therapeutics in various formats
- Experience with managing antibody discovery and protein production at CROs
- Demonstrated experience leading, mentoring and building effective teams as an enthusiastic, resourceful, and effective people manager
- Outstanding interpersonal and communication skills with the ability to work effortlessly and cross-functionally with multiple teams, academic collaborators and partners
- Highly motivated strong team player who enjoys working in a fast-paced, inclusive, ethical, team-oriented, multidisciplinary environment of a small biotech
Responsibilities
- Direct early-stage discovery biologics engineering programs that deploy the Ampersand technology platform
- Guide project leads in the Protein Sciences team to design engineered proteins, monoclonal/bispecific antibodies and other biologics of interest to the company
- Contribute scientific expertise to strategic decision making and technical innovation within the Protein Sciences group
- Drive program-specific protein development strategies while contributing to broader platform development and long-term protein sciences roadmap
- Successfully collaborate across the company to effectively achieve experimental and organizational goals and ensure protein production is aligned to needs of projects and other groups
- Identify and integrate state-of-the-art technologies to further enhance the capabilities and throughput of the Protein Sciences group
- Balance external (CRO) and internal resources to solve problems and drive progress
- Oversee biologics developability and collaborate on CMC efforts for advanced molecules
- Provide leadership and coordination to the team and provide direction for their career development
- Present results and conclusions to the team/ company and at conferences
- Work closely with the Heads of Computational Biology and Discovery Biology in Boston, US in addition to antibody discovery leaders in Pilsen, CZ
- Report to the CSO, and will be a member of Scientific Leadership team
Preferred Qualifications
- Experience with antibody design and discovery: immunization and display based techniques
- Experience with driving biologics programs to development candidates and clinical trials; experience with conducting developability studies and CMC activities