Senior Director – Computational Biology
| Company | Acadia Pharmaceuticals |
|---|---|
| Location | San Francisco, CA, USA, Princeton, NJ, USA, San Diego, CA, USA |
| Salary | $234000 – $292200 |
| Type | Full-Time |
| Degrees | PhD |
| Experience Level | Senior |
Requirements
- PhD in Bioinformatics, Computational Biology, Genomics, Computer Science or related field
- Targeting 8 years of experience, including a minimum of 4 years in the pharmaceutical or biotech industry
- Experience leading teams of biostatisticians/data scientists
- Extensive experience analyzing and integrating large, multivariate data sets
- Experience in target discovery, predictive/response biomarker identification and translational research
- Secure management of sensitive internal data and protected health information in cloud-based computing environments
- Secure deployment of web-based applications in cloud servers
- Proficiency in machine learning algorithms, exploratory data analysis and statistical modeling techniques
- Proficiency in programming languages including R, Python and bash
- Excellent communication (oral and written) skills, interpersonal skills, project management and cross-functional teamwork
- Must be able to travel domestically and/or internationally on occasions
Responsibilities
- Provide computational support for pre-clinical, translational and clinical scientists in the efforts of discovery biology, translational research and clinical biomarker studies
- Develop and implement bioinformatic algorithms for integrative analysis and visualization of multi-omics data from various sources and data modalities such as bulk or single-cell RNA-Seq, targeted exome and whole genome sequencing, proteomics and other biomarker signals from cell culture, in vivo studies, and clinical serum, blood and tissue biopsies
- Develop interactive and secure web applications in R Shiny and/or Python Streamlit to make complex analysis pipelines and database queries accessible to non-bioinformatic scientists
- Support research scientists in the analysis and visualization of multivariate data for internal and external presentations to key opinion leaders, at scientific conferences and to external stakeholders throughout the process of developing strategic partnerships
- Provide oral presentations to internal and external audiences on research results across all stages of drug development in formal settings and at regular company meetings
- Where appropriate, support the translational/clinical research/medical affairs teams in conducting analyses and providing visualizations for investor presentations, investigator brochures, site initiation visits and safety review boards
- Perform other duties as assigned
Preferred Qualifications
-
No preferred qualifications provided.