Senior Associate Scientist – Therapeutic Cargo Design – In-Vitro
| Company | Regeneron Pharmaceuticals |
|---|---|
| Location | Tarrytown, NY, USA |
| Salary | $79100 – $129100 |
| Type | Full-Time |
| Degrees | Bachelor’s, Master’s |
| Experience Level | Senior |
Requirements
- BS/MS in biology, molecular biology, genome sciences, biochemistry, or a related field
- 3+ years of relevant experience in an academic or industry laboratory in a relevant field
- Fundamental understanding of molecular and cellular biology
- Experience with basic molecular biology techniques such as cell culture, western blot, PCR, cloning, etc.
- Experience with flow cytometry
- Knowledge regarding adeno-associated virus (AAV) vector-based gene therapy methods and technologies
- Familiarity with in vivo experimentation and basic mouse husbandry
- Highly organized, enthusiastic, and able to manage multiple projects
Responsibilities
- Performing cell-based assays using transfection and viral vector transduction techniques in BSL2 mammalian cell culture and analyzing transfection efficiency using flow cytometry
- Performing RNA and DNA isolation and purification from cell culture and tissue samples
- Performing molecular biology experiments using qPCR, dPCR, and ddPCR
- Developing and implementing ELISA and Western blot-based protein expression analysis assays
- Producing, purifying, quantifying, and characterizing AAV vectors
- Analyzing and presenting data (familiarity with Graphpad Prism or other statistical/graphical software)
- Collaborating with therapeutic-focused groups to characterize and optimizing construct designs based on functional activity in various in vitro and in vivo models
- Participating in team meetings and preparation of presentations for departmental meetings
- Maintaining accurate documentation of experimental procedures, data, and analysis, including meticulous sample tracking and data management
Preferred Qualifications
- Enjoy working in an innovation driven, highly collaborative, and fast paced environment
- Have an affinity for technology development-focused projects
- Skilled at designing well-controlled experiments that can provide reliable results
- Can effectively balance multiple projects independently and across groups
- Possess strong organizational and time-management skills