Scientist-Viral Delivery Technologies
Company | Regeneron Pharmaceuticals |
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Location | Tarrytown, NY, USA |
Salary | $92500 – $151100 |
Type | Full-Time |
Degrees | Bachelor’s, Master’s |
Experience Level | Senior |
Requirements
- BS/MS in cell biology, molecular biology, biochemistry, or related field
- 6+ years of relevant experience
- Experience with mammalian cell culture
- Manipulation and purification of viruses or proteins
- DNA isolation from tissue and cells
- Plasmid cloning
- Use of antibodies for various applications
- Ability to maintain accurate, up-to-date electronic lab records
Responsibilities
- Designing, driving, analyzing, and troubleshooting in vitro experiments to characterize and validate antibody-retargeted viral vector designs and screening protocols
- Performing basic molecular biology and protein analysis techniques (Cloning, SDS PAGE analysis, Western blotting, ELISA, DNA extractions, PCR, quantitative PCR, protein chromatography, etc.)
- Working closely with bioinformatics team to translate data mining insights into vector engineering designs
- Executing rAAV production protocols and further developing our understanding of AAV biology to inform novel vector optimizations
- Working collaboratively with other department team members, collaborators in various analytical groups and core facilities across research and discovery
- Participation in team meetings and preparation of regular presentations for departmental meetings
Preferred Qualifications
- Familiarity with key antibody properties
- Protein engineering
- Viral vector production
- Relevant research associated software (i.e. Microsoft Office, GraphPad Prism, Benchling, MacVector)
- Publicly available online resources (NCBI, Uniprot, RCSB Protein Data Bank, etc.)