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Principal Scientist Quantitative Systems
| Company | Sanofi |
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| Location | Cambridge, MA, USA |
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| Salary | $122250 – $176583.33 |
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| Type | Full-Time |
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| Degrees | PhD |
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| Experience Level | Senior |
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Requirements
- PhD with an excellent track record of productivity in the areas of systems pharmacology/biology, computational biology, biomedical engineering or related field, as manifested by publications and scientific presentations in conferences
- At least 2 years of Postdoctoral experience in disease modeling/QSP
- Proficiency in mathematical modeling using differential equations
- Extensive experience in computational tools such as MATLAB, Julia and R (MATLAB preferred)
- Excellent oral and written communication skills
- Ability to quickly learn pathophysiology in indications of interest, and treatment approaches in immunology
- Highly motivated, detail-oriented, and independent researcher
- Able to thrive in a collaborative, multi-disciplinary team environment
- Strong commitment to on-the-job-training
Responsibilities
- Function as part of a team to develop and apply multiscale computational models of complex diseases based on detailed biological mechanistic knowledge to support model-informed drug discovery & development
- Survey literature to gain understanding of critical physiological processes to be represented, and identify suitable mechanistic elements, data, parameters and assumptions to be included
- Identify and analyze suitable internal preclinical and clinical data to inform modeling activities
- Analyze simulation results and identify appropriate strategies to resolve issues pertaining to model performance and accuracy
- Maintain extensive documentation of model development process, and data analysis
- Maintain quantitative systems pharmacology expertise through comprehensive education
- Communicate modeling predictions to key stakeholders
Preferred Qualifications
