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Postdoctoral Fellow – Immuno-Oncology Discovery
| Company | AstraZeneca |
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| Location | Gaithersburg, MD, USA |
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| Salary | $99900 – $107500 |
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| Type | Full-Time |
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| Degrees | PhD |
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| Experience Level | Junior, Mid Level |
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Requirements
- PhD in Biology or related field
- A maximum of 4 years of postdoctoral experience
- Strong immunology and tumor biology experience
- Proficient in animal model development
- Expertise in assays and models to study T cell function in vivo
- Extensive experience with multi-color flow cytometry to characterize T cell populations
- Strong planning, organizational, and time management skills
- Proven track record of publication in scientific journals and experience in oral presentations
Responsibilities
- Develop in vitro assays and in vivo syngeneic models to investigate the contribution of T cell subsets to T Cell Engager function
- Dissect the role of T Cell Engagers on immune cell function, migration, and maintenance in syngeneic animal models
- Leverage core technology platforms (single-cell proteomic and genomics, multi-fluorescence imaging, spatial transcriptomics) to dissect immune responses in vivo
- Collaborate with biologics engineers to design new T Cell Engagers and test new hypotheses
- Plan, write, and publish high-quality scientific papers and present at key conferences
Preferred Qualifications
- Experience with cell culture and functional in vitro assays
- Familiar with antibody structure and protein engineering strategies is a plus
- Understanding of high-dimensional analyses (flow cytometric or genomic) is preferred
- Experience with spatial analyses (multi-fluorescent imaging or spatial transcriptomics) is an advantage
- Self-driven, results-oriented, and highly motivated individual
- Ability to independently design research plans and critically analyse experimental results
- Strong interpersonal and collaboration skills
