Associate Principal Scientist - Imaging

Associate Principal Scientist – Imaging

Master’s (with 8+ years) or Ph.D. (with 4+ years) in biology, pharmacology, radiopharmaceutical sciences or related field and relevant work experience in the area of radiopharmaceutical discovery
Design, optimization, and implementation of radioligand binding experiments in tissue homogenate
Design, optimization, and implementation of autoradiography experiments on tissue slices
Sectioning of frozen tissue for autoradiography experiments
Ability to independently design, execute and interpret in vitro radioligand binding experiments
Analysis and interpretation of data from in vitro binding experiments using graphical nonlinear curve fitting software methods
Theoretical knowledge of ligand-receptor binding interactions and their application to drug discovery
Proven track record of generating publication quality data and contributing to manuscript or patent preparation
Highly developed oral and written communication skills and keen ability to engage internal and external team members in collaborative research
Self-motivated and resourceful with good interpersonal skills
Ability to independently manage workflow to see projects through from start to completion
Strong interpersonal, verbal and written communication skills
Willingness and ability to work with radioactive materials including ³H, 18F, and/or 89Zr
Strong record keeping skills
Demonstrates a high level of attention to detail

Design, optimize and perform in vitro radioligand binding assays, including autoradiography and tissue homogenate binding assays, to assess the binding characteristics of radioligands to support PET tracer discovery and development
Analyze, interpret results and draw conclusions from experiments, and suggest, design, and pursue relevant experiments
Generate reliable and reproducible data in a timely manner
Present results and next steps at group meetings and project meetings
Access and understand relevant scientific literature and apply theoretical framework to solving problems within scientific discipline in a timely manner
Work effectively with other scientists as part of a collaborative, multidisciplinary team