Sr. Scientist – Analytical R&D
| Company | Merck |
|---|---|
| Location | North Wales, PA, USA |
| Salary | $Not Provided – $Not Provided |
| Type | Full-Time |
| Degrees | Bachelor’s, Master’s, PhD |
| Experience Level | Senior, Expert or higher |
Requirements
- Ph.D. degree in analytical chemistry, chemistry, biochemistry, biomedical engineering or related field (with expected graduation no later than August 2025) or M.S. degree with a minimum of 4 years of experience in the Biotech/Pharmaceutical Industry, or B.S. degree with a minimum of 8 years of experience in Biotech/Pharmaceutical Industry.
- In-depth knowledge and understanding of separation science (HPLC, CE, LC-MS, SDS-PAGE, & WB) demonstrated by publications.
- Extensive experience with UPLC/HPLC analysis of biologics or vaccines (e.g. SEC, RP, IEX) and CE techniques.
- A strong team player with excellent oral and written communication skills; ability to work both independently for development of assays and cross-functionally.
- Demonstrated scientific ability through publications and presentations in scientific conferences.
Responsibilities
- Solve complex analytical problems at the interface of biology, chemistry, and lab informatics disciplines to enable development of Vaccines.
- Develop state-of-the-art analytical techniques, such as separations of small molecules, polymers, proteins, conjugates, and nanoparticles (UPLC/HPLC, and CE), spectroscopic techniques, virology, and classical wet chemistry techniques.
- Collaborate with a team of scientists in vaccine investigations and method lifecycle management.
Preferred Qualifications
- Experience with qualification, validation, and transfer of assays to a GMP or regulated laboratory environment as described in ICH Q2 and USP
- Experience in representing analytical functional area on project teams.
- Authoring and reviewing internal technical reports, sections of regulatory filings (e.g. IND, BLA) and external scientific publications.
- Strong ability to deliver complex objectives under aggressive timelines in a rapidly changing environment.
- Ability to design, execute and/or direct development and qualification of release, characterization, and stability assays for testing of clinical trial material and in support of product and process development.