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Associate Director – In Vivo Pharmacology – Oncology R&D
| Company | AstraZeneca |
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| Location | Gaithersburg, MD, USA |
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| Salary | $134892.8 – $202339.2 |
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| Type | Full-Time |
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| Degrees | Master’s, PhD |
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| Experience Level | Expert or higher |
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Requirements
- MS or Ph.D. in relevant field and at least 10 yrs (Ph.D.) or 15 yrs (MS) related post-degree experience
- Experience developing and working with complex in vivo models, such as xenograft, patient derived xenograft (PDX), syngeneic and orthotopic mouse models
- Experience delivering in vivo pharmacology studies in mouse tumor models, including dose-finding tolerability studies, PK/PD and efficacy studies
- In-depth knowledge of ADCs and oncology disease area biology (solid tumors); experience with both ADC and immuno-oncology assets
- Experience in preparing pharmacology project packages for internal milestone transitions and IND filings which exemplify a clear communication style
- Ability to act as an external ambassador and to influence external organizations to enhance the image and reputation of AstraZeneca
- Highly developed problem solving and risk management skills, and attention to detail
- Strong interpersonal, collaborative and team building skills
Responsibilities
- Develop, design, and analyze both in vivo and in vitro experiments to assess the function of candidate oncology drugs and dissect the mechanism of action of novel cancer therapeutics
- Collaborate with cross-functional teams including representatives from biosciences, translational medicine, clinical, drug metabolism, pharmacokinetics, and safety to help understand the translatability of in vivo research to the clinic
- Work collaboratively with project leaders to ensure the timely generation, and dissemination of critical program data
- Contribute to scientific publication goals
Preferred Qualifications
No preferred qualifications provided.
