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Sr Supervisor – Vector Production

Sr Supervisor – Vector Production

CompanyTwist Bioscience
LocationTualatin, OR, USA
Salary$Not Provided – $Not Provided
TypeFull-Time
DegreesBachelor’s
Experience LevelSenior

Requirements

  • B.S. in Molecular Biology, Biochemistry, Chemistry, or a closely-related field.
  • At least 2 years of relevant industry or research experience in Molecular Biology, Biochemistry, Chemistry or a closely-related field.
  • Must have a strong background in molecular biology techniques including purification (DNA and protein), DNA quantification, PCR, enzymatic and cell based assays, and molecular cloning.
  • Excellent interpersonal skills. Respectful and open to others’ views; contributes to building a positive team spirit.
  • Proficient in writing and communicating in English. Able to present data effectively.
  • Able to prepare documents including data summaries, technical and analytical reports.
  • Comfortable working in a LEAN manufacturing / controlled laboratory environment.
  • Self-motivated and passionate about delivering world-class DNA-based products.

Responsibilities

  • Lead, mentor, and supervise a team of Manufacturing Associates involved in mRNA production and specialty production activities.
  • Manage team performance, including setting goals, providing feedback, conducting performance reviews, and fostering a positive and productive work environment.
  • Oversee the entire mRNA/specialty production process, from raw material handling to final product delivery.
  • Work with R&D to scale up new mRNA constructs and processes.
  • Ensure production activities are carried out in accordance with established Standard Operating Procedures (SOPs), safety guidelines, and regulatory requirements (e.g., cGMP).
  • Manage the execution of complex and non-standard production orders, including process development, optimization, and troubleshooting.
  • Monitor production yields, efficiency, and quality metrics, and implement corrective actions as needed.
  • Ensure all production activities adhere to the highest standards of quality and compliance, including cGMP regulations.
  • Collaborate effectively with other departments, including Research and Development, Quality Assurance, Supply Chain, and Project Management, to ensure seamless production operations.

Preferred Qualifications

  • Experience working with lab automation
  • Experience with mRNA and other molecular biology techniques
  • Experience using LIMS
  • Experience working with mammalian culture is highly desirable