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Senior/Research Associate – Metabolism
| Company | NewLimit |
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| Location | San Bruno, CA, USA |
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| Salary | $60000 – $98000 |
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| Type | Full-Time |
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| Degrees | Bachelor’s, PhD |
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| Experience Level | Senior |
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Requirements
- BS in cell biology, endocrinology, molecular biology, or a related natural science and 2+ years of work experience in a cell/molecular biology laboratory (academic or industry setting) or PhD in cell biology, endocrinology, molecular biology, or a related field
- Proficiency in animal handling and husbandry techniques for rodent models (mice or rats)
- Proficiency in molecular biology and molecular cloning methods
- Exceptional organizational skills, as demonstrated by detailed record-keeping in lab notebook and an ability to effectively carry out multiple ongoing projects or experiments
Responsibilities
- Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test epigenetic reprogramming interventions for aged and diseased hepatocytes
- Isolate murine and human hepatocytes using perfusion, FACS, and gradient based approaches
- Reprogram hepatocytes ex vivo and in vivo
- Perform experiments in pre-clinical liver disease animal models
- Perform functional and phenotypic assays to evaluate the effects of reprogramming on hepatocyte biology
Preferred Qualifications
- Proficiency with mammalian cell culture
- Experience working with mouse models of liver dysfunction
- Experience with ex vivo culture and manipulation of hepatocytes
- Experience with single cell genomics methods
