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Scientist – Cancer Metabolism
Company | Calico Labs |
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Location | San Bruno, CA, USA |
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Salary | $127000 – $155000 |
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Type | Full-Time |
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Degrees | PhD, MD |
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Experience Level | Mid Level, Senior |
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Requirements
- PhD or MD/PhD in cell/molecular biology, biochemistry or a related field with 0-5 years of postdoctoral and/or industry experience
- Experience working with animal models to study human disease
- Deep knowledge of cellular and organismal metabolism and physiology
- Strong working knowledge of genetics, cell biology and molecular genetics
- Detail-oriented, organized and driven
- A track record of strong research productivity
- Strong teamwork and communication skills
- Flexible, able to respond quickly to shifting priorities and able to multitask
- Must be willing to work onsite five days per week
Responsibilities
- Perform basic research to determine the role of metabolic interactions in tumor progression, metastasis to specific organs and therapy resistance
- Develop approaches to evaluate metabolic interactions between specific cell types during tumor progression and metastasis
- Publish papers and present findings both internally and at scientific conferences
Preferred Qualifications
- Experience with mass spectrometry to measure metabolites and/or lipids and/or proteins
- Experience using stable isotope labeling to understand metabolic fluxes in vitro and/or in vivo
- Experience with cancer mouse models
- Experience with mouse models of brain tumors
- Experience in pediatric tumor biology
- Experience with integrating multiomics data
- Competence with mammalian tissue culture, in vitro gene editing techniques (CRISPR/Cas9, viral transduction) and basic molecular biology methods
- Familiarity with R or Python for data analysis and visualization