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Senior Research Associate – DNA Assembly

Senior Research Associate – DNA Assembly

CompanyFlagship Pioneering
LocationCambridge, MA, USA
Salary$Not Provided – $Not Provided
TypeFull-Time
DegreesBachelor’s, Master’s
Experience LevelMid Level, Senior

Requirements

  • MSc in Molecular Biology, Biotechnology, or a related field with 3+ years, or BSc with 5+ years, of high-throughput DNA production experience or related experience. Industry experience strongly preferred.
  • Hands-on expertise in molecular biology techniques, including cloning, DNA synthesis, and sequencing.
  • Experience with Illumina sequencing and library construction.
  • Experience working in high-throughput production environments with a focus on scalability and efficiency.
  • Familiarity with integrated laboratory automation technologies and their application in DNA production workflows.
  • Proven ability to identify and resolve process inefficiencies and implement phased improvements.
  • Strong data analysis skills and ability to interpret workflow performance metrics.
  • Excellent communication and collaboration skills, with a proven ability to work effectively across interdisciplinary teams.

Responsibilities

  • Identify and address sources of variation in high-throughput DNA production workflows to enhance efficiency, reliability, and scalability.
  • Integrate and optimize custom automation technologies to streamline production processes.
  • Collaborate with the members of the Nucleic Acids team and our Data Sciences and Machine Learning groups to onboard new workflows, resolve bottlenecks, and improve data systems.
  • Write, implement, and maintain Standard Operating Procedures (SOPs) for both existing and new lab processes.
  • Conduct data analysis and interpretation to monitor lab processes and drive process improvements.
  • Provide operational leadership within the lab, coordinating activities and ensuring smooth execution of production workflows.

Preferred Qualifications

  • Experience in designing and optimizing DNA assembly workflows for synthetic biology applications.
  • Experience with assembling high diversity DNA libraries.
  • Familiarity with digital systems and data pipelines used in high-throughput environments.
  • Demonstrated ability to write technical documentation, such as SOPs and validation reports.
  • Knowledge of best practices for lab operations and experience mentoring team members.