Director – Cardiometabolic Diseases – Inflammation – And Obesity – Translational Biology
| Company | Valo Health |
|---|---|
| Location | Lexington, MA, USA |
| Salary | $Not Provided – $Not Provided |
| Type | Full-Time |
| Degrees | PhD |
| Experience Level | Expert or higher |
Requirements
- A PhD in Biological Sciences or a related field with 10+ years of experience (may include postdoctoral experience or MS with 14+ years or BS with 16+ years) and deep expertise in inflammation plus one or more of the following, obesity, diabetes, adipose tissue, liver, cardiovascular.
- Expertise with in vivo, ex-vivo, and in vitro systems including cell culture, molecular biology, genetic manipulation, and development of functional cellular assays.
- Experience leading early and established preclinical stage drug discovery programs.
- Experience managing teams and scientists in a matrixed fashion to produce high quality data.
- Strong oral and written communication, presentation and interpersonal skills.
- Experience in collaborating with multidisciplinary teams including chemists, computational scientists, and various drug discovery experts.
- Track record of impactful scientific contributions as demonstrated through prior success in progressing programs through a therapeutic pipeline.
Responsibilities
- Serve as research project lead on various stage preclinical drug discovery projects.
- Provide thought leadership and guidance on the role of inflammation and the immune system in obesity, T2D, and/or cardiovascular disease biology, staying abreast of emerging trends and advancements in the field.
- Designing and executing translational biology plans to demonstrate in vitro/in vivo correlation including pk/pd assessments, profiling of cells and tissues by various methodologies, and identification/demonstration of tractable cellular and in vivo biomarkers.
- Designing efficacy experiments to coordinate and manage with CROs.
- Generate hypothesis-driven experimental plans and proposals for target validation in close collaboration with data scientists and other subject matter experts to enable crisp decision making.
- Manage scientists and teams in a matrixed manner to ensure high quality data generation and timely delivery of key readouts supporting team goals.
- Work in collaboration with Valo’s tissue and cell model experts to support ongoing drug discovery projects.
Preferred Qualifications
- Experience working with external stakeholders collaboratively.
- Experience in assessing novel biology and cellular systems to aid in drug discovery programs and de-risking novel target concepts.
- Experience working with biobanks and Real-World Evidence teams to generate supporting human centric evidence and novel biomarker concepts.